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#dopamine

2 posts2 participants0 posts today
Public
Albert Cardona

"Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion" by Toshima et al. (Michael Schleyer) 2025
biorxiv.org/content/10.1101/20

bioRxiv · Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotionTwo evolutionary highly conserved functions of dopamine are to carry "teaching" signals during associative learning and to control movement. In mammals and humans these functions are generally thought to be produced by different populations of neurons. Here, we investigated in the larva of Drosophila melanogaster whether both these functions can be induced by the same individual dopaminergic neurons in the central brain. Focusing on the dopaminergic neurons of the DL1-cluster, we asked whether the optogenetic activation of individual neurons established associative punishment and/or safety memories, controlled the retrieval of the established memories, and acutely modulated locomotion. We found that each neuron had a unique, yet overlapping set of behavioural effects. Several individual neurons both established a memory and modulated acute locomotion by increasing the animals' bending and decreasing its velocity. Our results demonstrate that individual dopaminergic neurons can fulfil a surprisingly broad range of functions in different behavioural contexts. Given the highly conserved roles of the dopaminergic system across the animal kingdom, this study raises the question whether a similarly diverse functionality can be found also in other animals, including humans. ### Competing Interest Statement The authors have declared no competing interest.
#neuroscience#Drosophila#dopamine
Public
MediaFaro News Digest

French parliament to probe psychological effects of TikTok on children.

French lawmakers have approved the creation of a commission of enquiry to examine the psychological effects of TikTok on children and teenagers.

The video platform is particularly prized by youngsters.

mediafaro.org/article/20250314

RFi · French parliament to probe psychological effects of TikTok on children.By RFi
#TikTok#France#SocialMedia
Public *
datum (n=1)

TLDR: Pandas are dope fiends!?

TIL that 🐼 Pandas aren't born loving 🎍bamboo, but that it's an addiction with a dopamine component.

Those cute furry pandas are actually carnivores. 🍖

But they sit on their butts all day eating plants 🌿 and getting 🌀👃🌀 high instead of chasing animals. 🐁

Quote: "some of the bamboo-derived miRNAs were found to regulate dopamine pathways, driving food motivation and the reward system linked to it. So if eating bamboo is a pleasurable, satisfying experience for a panda, it's more likely to be solely driven to seek out this trigger." newatlas.com/biology/pandas-ba

Pandas! :pandahype: :pandabighype:

New Atlas · Pandas "tricked" into becoming the world's biggest bamboo fansBuilt to be carnivorous, giant pandas spend up to 16 hours a day on their backsides eating bamboo. But contrary to all the panda jokes, it's not because they're lazy or too dumb to know better. It's far more fascinating – and it may help humans, too.
#drugs#dopamine#pandas
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♡ Eva Winterschön ♡

Saturday (yesterday), just another February

⚕️Rapid Serotonin Shock Syndrome ⚕️

* 16:00,0: recovery from NoroV ongoing
* 16:30,0: proximal awareness shifts to five meter spherical
* 16:30,30: ocular signals go dark
* 16:30,32: ocular signals return with cross-chiasmic jitter + non-rhythmic phase-shift
* 16:32,0: rhythmic visual blur/focus in-line with cerebral alpha-waves
* 16:36,0: perception of time now slow-frame-rate, visual tracers/long-tail, tactile sensory-processing latency increase
* 16:38,0: awareness of intense fever, head + upper torso rapid profuse sweating, tremor amplification
* 16:38,30: whole body shivering, unable to tell if sweat is hot or cold, temperature
* 16:39,0: hypoglycemia begins
* 16:39,30: ingest neuro-mitigation Rx + insulin + glucose + somatropin + ice cream
* 16:40,0: lay down, wrapped in light blanket, instant blackness returned to the void
* 22:22,0: awoken externally, liquids + light calories, move to bed
* 01:44,0: awoken by autonomic distress.. here come the Rx, aversion to sleep - reminds me of the coma
* 05:08,0: stop reading research on neuro-cognitive and neuro-pharmacology topics of interest. attempt sleep.

#medical #minorEmergency #serotonin #dopamine #brain #neurology #neurotransmitters #norovirus
#brain #healthcare #saturday #sunday #morning

Public *
ItsCarryl

I spent a few happy hours getting partway into the info-collation for a blog post. Shaking off the notion of it being weird, silly, etc to be listing ages of an actor and each of his characters as if many people care when I realised how nice it was to have something to focus on. Lately my desire for the house-clearance marathon has stalled, as has art, gaming, you name it. The #AuDHD #brain has its wants and needs.

#hyperfocus#hyperfixation#SpecialInterest
Public
Peter

Anyone else have days where they feel like their cancer isn't really cancer-y enough?

Like some sort of super twisted imposter syndrome?

(Or rather *exactly normal* imposter syndrome applied in an unconventional way.)

No?

Just me?

Cool, cool.

Time to go lift something heavy.

#Dopamine
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