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#cell

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Rxiv mechanobio

📰 "A Navier-Stokes-Peridynamics hybrid algorithm for the coupling of compressible flows and fracturing materials"
arxiv.org/abs/2504.11006 #Physics.Comp-Ph #Dynamics #Cell

arXiv.orgA Navier-Stokes-Peridynamics hybrid algorithm for the coupling of compressible flows and fracturing materialsModeling and simulation of fluid-structure interactions are crucial to the success of aerospace engineering. This work addresses a novel hybrid algorithm that models the close coupling between compressible flows and deformable materials using a mesoscopic approach. Specifically, the high-speed flows are described by the gas-kinetic scheme, which is a robust Navier-Stokes alternative solver built on the molecular kinetic theory. The deformation, damage, and fracture of materials are depicted using the bond-based peridynamics, which serves as coarse-grained molecular dynamics to construct non-local extensions of classical continuum mechanics. The evolution of fluids and materials are closely coupled using the ghost-cell immersed boundary method. Within each time step, the solutions of flow and solid fields are updated simultaneously, and physics-driven boundary conditions are exchanged for each other via ghost cells. Extensive numerical experiments, including crack propagation in a pre-cracked plate, subsonic flow around the NACA0012 airfoil, supersonic flow around the circular cylinder, and shock wave impacting on the elastic panel, are performed to validate the algorithm. The simulation results demonstrate the unique advantages of current hybrid algorithm in solving fracture propagation induced by high-speed flows.
Public
Rxiv mechanobio

📰 "A role for Myosin in triggering and executing amnioserosa cell delaminations during dorsal closure."
biorxiv.org/content/10.1101/20 #Morphogenesis #Myosin #Cell

bioRxiv · A role for Myosin in triggering and executing amnioserosa cell delaminations during dorsal closure.The remodeling of epithelial tissues is a critical process in morphogenesis, often involving the apoptotic removal of individual cells while preserving tissue integrity. In Drosophila, the amnioserosa, a highly dynamic extra-embryonic tissue, undergoes extensive remodeling, culminating in its complete elimination at the end of dorsal closure. While apoptotic cell delaminations in the amnioserosa have been proposed to contribute to dorsal closure, the cellular mechanisms underlying this process remain poorly understood. In this study, we have investigated actomyosin dynamics during cell delaminations and analyzed the consequences of perturbing non-muscle Myosin activity globally in the entire tissue as well as locally in groups of cells. We found that Myosin plays an essential role in both triggering and executing cell delaminations, with high Myosin contractility promoting cell extrusion even in the absence of caspase activity. Additionally, our results suggest that cell delaminations are governed by both cell-autonomous Myosin dynamics and mechanical cues from the tissue environment. Together, these findings provide new insights into the regulation of epithelial cell removal and the complex interplay between apoptotic and mechanical signals during tissue remodeling. ### Competing Interest Statement The authors have declared no competing interest.
Public
ap.galerie
animalis lucivoris, hey.

- composants électroniques, cuivre, plexiglas, bois - 2022

Balise lumineuse émettant "hey" en code morse après avoir accumulé suffisamment d'énergie ; alimentation par panneau solaire (si besoin par pile bouton).

Light marker which blinks "hey" in morse code after having stored enough energy ; power supply by solar cell (if necessary, by button cell).

#electronic #pcb #transistor #photovoltaic #cell #standalone #lowenergy #storage #morse #code #light #blink #hey #useless #device
#art #techart #lyon #ap22
#ap22
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